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Describe a service in plain words, or type a CPT/HCPCS code.

Medicare's 500 most-billed CPT codes of 2021

In CY2021 Medicare paid $82.1B across these 500 CPT codes. 99214 (Established Patient Office Visit, Level 4) leads every measure: 25.3M beneficiaries and $12.0B allowed. Below the top few the rankings split apart. The codes that reach the most patients are rarely the ones that move the most money.

Allowed
$82.1B
Total Medicare allowed dollars
Services
1.2B
Times these codes were billed
Top 25
57.2%
Share of the allowed dollars
Vintage
CY2021
Medicare fee-for-service only

All 500 codes, ranked

Sorted by allowed per service. Every code links to its full rate breakdown.

Sort by: Overall rank Beneficiaries Services Allowed dollars Allowed per service
# Code What it is Beneficiaries Services Allowed Per service
451 37231 — Retired after Q4 2025 2,631 3,111 $38,578,540 $12,400.69
104 37227 Thigh Artery Stent with Atherectomy Retired after Q4 2025 17,305 21,076 $210,339,593 $9,980.05
66 37229 Below-Knee Artery Atherectomy, First Vessel Retired after Q4 2025 27,616 38,847 $314,096,780 $8,085.48
70 63685 Spinal Cord Stimulator Generator Implant 26,206 43,936 $297,253,121 $6,765.59
95 37225 Thigh Artery Atherectomy Retired after Q4 2025 32,172 41,240 $228,643,498 $5,544.22
219 64590 Peripheral or Gastric Nerve Stimulator Generator Implant 15,325 20,484 $93,518,365 $4,565.43
362 36906 Dialysis Access Clot Removal with Stent Placement 8,702 11,713 $49,040,440 $4,186.84
327 36903 Dialysis Access Stent Placement, Peripheral Segment 13,780 17,581 $57,017,311 $3,243.12
341 22514 Lumbar Vertebral Augmentation (Kyphoplasty) 20,917 22,958 $53,510,804 $2,330.81
374 22513 Thoracic Vertebral Augmentation (Kyphoplasty) 18,159 20,630 $47,811,319 $2,317.56
432 64561 Sacral Nerve Stimulator Electrode Placement 10,245 17,819 $40,702,778 $2,284.23
236 36482 Adhesive Closure of a Leg Vein, First Vein 24,658 45,708 $87,292,584 $1,909.79
336 36905 Dialysis Access Clot Removal with Angioplasty 19,519 32,625 $54,576,538 $1,672.84
562 55874 Prostate Spacer Gel Placement 17,779 17,882 $29,541,786 $1,652.04
239 36465 Foam Sclerotherapy of a Main Leg Vein 28,619 55,054 $86,034,423 $1,562.73
348 33249 Implantable Defibrillator System Placement 32,774 33,692 $51,902,317 $1,540.49
292 65778 Amniotic Membrane Placement on the Eye Surface 25,263 43,923 $65,301,578 $1,486.73
560 37226 — Retired after Q4 2025 18,388 20,218 $29,748,875 $1,471.41
409 25609 Open Repair of Complex Distal Radius Fracture 18,604 29,961 $43,738,544 $1,459.85
338 67042 Vitrectomy with Internal Limiting Membrane Peel 24,652 41,527 $54,117,882 $1,303.20
272 22551 Anterior Cervical Discectomy and Fusion, One Level 32,633 54,568 $71,090,899 $1,302.79
568 65756 Endothelial Corneal Transplant 10,956 22,450 $29,189,257 $1,300.19
529 67108 Retinal Detachment Repair by Vitrectomy 15,151 25,380 $32,622,160 $1,285.35
115 78492 Cardiac PET Perfusion Imaging, Rest and Stress 135,770 148,785 $190,321,302 $1,279.17
190 36475 Radiofrequency Vein Ablation, First Vein 48,480 87,333 $108,982,682 $1,247.90
458 37228 — Retired after Q4 2025 26,636 31,140 $37,747,629 $1,212.19
285 22633 Lumbar Fusion, Posterior Plus Interbody, One Level 34,142 56,672 $68,442,028 $1,207.69
41 27447 Total Knee Replacement 256,757 468,498 $557,061,349 $1,189.04
233 33533 Coronary Bypass Using a Single Arterial Graft 47,518 77,111 $89,236,038 $1,157.24
420 77373 Stereotactic Body Radiation Therapy Delivery 7,608 36,447 $42,048,217 $1,153.68
274 93656 Catheter Ablation for Atrial Fibrillation (Pulmonary Vein Isolation) 59,976 61,730 $70,496,479 $1,142.01
570 55866 — 19,460 25,857 $29,172,286 $1,128.22
167 29827 Arthroscopic Rotator Cuff Repair 61,120 119,640 $134,727,698 $1,126.11
467 66174 Canaloplasty for Glaucoma, No Device Retained 12,455 33,500 $37,252,839 $1,112.03
67 27130 Total Hip Replacement 157,162 278,817 $309,642,418 $1,110.56
260 77523 Proton Beam Radiation Treatment, Intermediate Delivery 2,925 70,896 $77,407,270 $1,091.84
533 67036 Vitrectomy Through the Pars Plana 17,059 29,435 $31,984,490 $1,086.61
472 36478 Laser Vein Ablation, First Vein 20,439 34,865 $36,695,491 $1,052.50
208 27245 Hip Fracture Repair with Intramedullary Nail 75,917 100,025 $100,257,084 $1,002.32
130 36902 Dialysis Access Angioplasty, Peripheral Segment 92,673 175,168 $173,672,640 $991.46
207 23472 Total Shoulder Replacement 62,471 102,711 $100,678,059 $980.21
343 15260 Full-Thickness Skin Graft to Nose, Ear, Eyelid, or Lip 49,552 57,648 $53,505,427 $928.14
280 27236 Surgical Repair of Femoral Neck Fracture 54,385 76,466 $70,016,642 $915.66
154 77301 IMRT Treatment Planning 141,875 158,855 $144,704,715 $910.92
543 35301 — 24,716 34,562 $30,622,470 $886.02
534 29828 Arthroscopic Biceps Tenodesis 19,090 36,238 $31,958,527 $881.91
79 93229 Mobile Cardiac Telemetry, Technical Support and Surveillance 298,792 320,441 $278,801,542 $870.06
478 52601 TURP - Transurethral Prostate Resection 40,298 43,346 $36,244,304 $836.16
279 33361 Transcatheter Aortic Valve Replacement, Femoral Puncture 48,142 90,345 $70,123,663 $776.18
486 29880 Knee Arthroscopy, Meniscectomy Both Compartments 30,844 48,313 $35,672,509 $738.36
470 67904 Droopy Eyelid Repair, External Levator Approach 23,016 51,765 $36,895,932 $712.76
461 50590 Extracorporeal Shock Wave Lithotripsy 38,617 53,432 $37,472,119 $701.30
408 29881 Knee Arthroscopy with Meniscectomy 41,030 62,591 $43,772,129 $699.34
481 00567 Anesthesia for On-Pump Coronary Bypass Surgery 41,169 51,608 $35,877,949 $695.20
300 33208 Dual-Chamber Pacemaker Insertion 91,753 94,116 $64,231,980 $682.48
399 19301 Partial Mastectomy (Lumpectomy) 55,533 68,462 $44,630,109 $651.90
221 63047 Lumbar Laminectomy for Spinal Decompression 85,947 143,678 $93,056,947 $647.68
303 47562 Laparoscopic Cholecystectomy 81,792 100,985 $62,396,975 $617.88
53 78815 PET/CT Scan, Skull Base to Mid-Thigh 465,885 664,345 $409,417,307 $616.27
225 17313 Mohs Surgery, Trunk, Arms, or Legs, First Stage 125,921 159,602 $91,407,355 $572.72
49 17311 Mohs Surgery, Face and High-Risk Sites, First Stage 627,635 824,844 $471,073,161 $571.11
365 78816 PET/CT Scan, Whole Body 62,183 85,122 $48,552,658 $570.39
180 92928 Coronary Stent Placement, Single Major Vessel 168,257 207,993 $114,328,451 $549.67
571 29848 Endoscopic Carpal Tunnel Release 29,896 53,387 $28,926,420 $541.83
512 49650 Laparoscopic Repair of First-Time Inguinal Hernia 47,726 63,796 $34,078,232 $534.18
412 22842 Posterior Spinal Instrumentation, 3 to 6 Segments 51,576 83,291 $43,527,206 $522.59
548 22840 Posterior Spinal Instrumentation, Non-Segmental 36,822 59,587 $30,407,937 $510.31
263 64721 Carpal Tunnel Release 92,152 147,821 $74,824,415 $506.18
136 64635 Lower Back Facet Nerve Ablation, First Joint 189,408 367,445 $165,584,727 $450.64
366 52442 — 26,571 107,300 $48,266,396 $449.83
398 64633 Neck or Mid-Back Facet Nerve Ablation, First Joint 53,005 101,221 $45,167,024 $446.22
203 00670 Anesthesia for Major Spine and Spinal Cord Surgery 156,883 237,280 $101,358,624 $427.17
525 00560 Anesthesia for Heart Surgery Without Bypass Machine 59,535 77,245 $32,844,015 $425.19
531 28285 Hammertoe Correction 33,957 77,132 $32,535,192 $421.81
355 36561 Implanted Port with Tunneled Catheter, Age 5 and Over 116,219 123,592 $50,547,258 $408.98
113 17312 Mohs Surgery, Face and High-Risk Sites, Additional Stage 305,770 483,747 $196,642,752 $406.50
547 93460 — 79,118 80,580 $30,467,484 $378.10
37 90960 Monthly Dialysis Management, Adult, Four or More Visits 245,736 1,685,021 $614,835,794 $364.88
346 26055 Trigger Finger Release (Tendon Sheath Incision) 75,232 146,310 $52,223,038 $356.93
111 66982 Complex Cataract Surgery with Lens Implant 131,273 575,380 $198,564,020 $345.10
47 45385 Colonoscopy with Lesion Removal (Snare) 931,462 1,377,652 $471,376,733 $342.16
567 13101 Complex Wound Repair of the Trunk (Mid-Length) 77,843 87,964 $29,333,810 $333.48
276 95811 Sleep Study with CPAP or BiPAP Titration 188,346 215,256 $70,260,749 $326.41
318 13121 Complex Wound Repair of Scalp, Arms, or Legs (Mid-Length) 161,544 190,434 $59,798,418 $314.01
335 77338 Multi-Leaf Collimator Design for IMRT 140,466 176,793 $54,657,438 $309.16
312 95810 Attended Overnight Sleep Study in a Lab 180,192 197,362 $60,619,013 $307.15
501 19083 Breast Needle Biopsy with Ultrasound Guidance 110,070 113,831 $34,554,030 $303.56
134 90961 Monthly Dialysis Management, Adult, Two or Three Visits 188,301 561,285 $167,565,915 $298.54
197 90966 Monthly Home Dialysis Management, Adult 53,524 351,025 $104,729,636 $298.35
417 00537 Anesthesia for Cardiac Ablation and Electrophysiology Studies 93,710 141,685 $42,196,564 $297.82
514 36558 — 97,845 115,080 $34,076,911 $296.11
262 13132 Complex Wound Repair of Face, Neck, Hands, or Feet (Mid-Length) 227,085 264,997 $76,857,284 $290.03
489 77295 3D Conformal Radiotherapy Planning 109,585 124,388 $35,632,480 $286.46
395 55700 Prostate Needle Biopsy Retired after Q4 2025 138,805 163,271 $45,347,732 $277.75
423 43249 Upper Endoscopy with Esophageal Balloon Dilation 102,137 150,124 $41,550,456 $276.77
178 93458 Left Heart Catheterization with Coronary Angiography 401,515 422,027 $115,523,758 $273.74
538 11044 — 45,386 115,526 $31,118,041 $269.36
58 78452 Nuclear Stress Test, Heart Perfusion SPECT, Rest and Stress 1,426,034 1,479,390 $390,441,466 $263.92
309 01214 Anesthesia for Hip Replacement Surgery 162,357 235,803 $61,442,661 $260.57
250 12032 Layered Wound Repair, Trunk or Limbs (Mid-Length) 279,571 314,415 $81,825,811 $260.25
141 99496 Transitional Care Management, High Complexity 531,693 614,006 $159,686,682 $260.07
198 00790 Anesthesia for Upper Abdominal Surgery 273,249 405,976 $103,685,081 $255.40
88 64483 Transforaminal Epidural Injection, Lumbar/Sacral 465,451 998,200 $250,613,508 $251.07
205 01402 Anesthesia for Knee Replacement Surgery 275,770 412,203 $100,811,534 $244.57
65 45380 Colonoscopy with Biopsy 954,849 1,384,501 $323,947,432 $233.98
298 00840 Anesthesia for Lower Abdominal Surgery 189,347 276,718 $64,256,977 $232.21
357 64490 Neck or Mid-Back Facet Joint Injection, First Level 99,333 217,644 $50,305,772 $231.14
241 45378 Diagnostic Colonoscopy 302,029 383,846 $86,006,256 $224.06
147 64493 Lower Back Facet Joint Injection, First Level 300,300 657,100 $146,803,205 $223.41
483 65855 Laser Trabeculoplasty for Glaucoma 89,872 161,249 $35,846,840 $222.31
7 66984 Cataract Surgery with Lens Implant 1,116,308 8,957,671 $1,990,420,515 $222.20
19 99291 Critical Care, First Time Block 1,799,698 6,124,185 $1,359,264,890 $221.95
485 95819 EEG Recording Both Awake and Asleep 148,678 163,329 $35,833,061 $219.39
506 95911 Nerve Conduction Studies, 9-10 Studies 151,969 157,680 $34,238,182 $217.14
566 52332 Cystoscopy with Ureteral Stent Placement 96,760 136,097 $29,471,519 $216.55
434 77290 Complex Radiation Therapy Simulation 150,005 186,466 $40,322,894 $216.25
39 99205 New Patient Office Visit, Level 5 2,517,870 2,874,700 $614,242,295 $213.67
257 77280 Simple Radiation Therapy Simulation 119,244 374,272 $79,315,494 $211.92
523 01230 Anesthesia for Upper Thigh Bone Surgery 108,558 155,205 $32,855,808 $211.69
330 72197 Pelvis MRI, Before and After Contrast 233,983 265,444 $55,714,762 $209.89
349 62321 Neck or Upper Back Epidural Injection with Imaging 133,028 247,573 $51,694,875 $208.81
503 90962 — 73,161 167,870 $34,398,355 $204.91
182 11043 Wound Debridement Down to Muscle or Fascia 134,671 554,409 $112,081,002 $202.16
126 52000 Diagnostic Cystoscopy 671,819 880,672 $177,573,199 $201.63
13 99223 Initial Hospital Care, Level 3 3,711,248 9,223,414 $1,846,567,710 $200.20
537 88377 — 58,465 156,990 $31,204,628 $198.77
557 00320 — 97,149 149,974 $29,805,623 $198.74
145 62323 Lower Back Epidural Steroid Injection with Imaging 397,277 744,376 $147,643,741 $198.35
256 74183 MRI Abdomen, Before and After Contrast 334,821 404,552 $79,481,423 $196.47
469 93351 Stress Echocardiogram, Complete with Supervision 186,417 190,444 $36,923,420 $193.88
123 77427 Radiation Treatment Management, Per Five Sessions 229,607 939,991 $181,382,607 $192.96
200 74178 CT Abdomen and Pelvis, Before and After Contrast 463,910 537,326 $102,405,759 $190.58
176 99495 Transitional Care Management, Moderate Complexity 562,109 625,395 $119,127,118 $190.48
192 31231 Diagnostic Nasal Endoscopy 396,467 565,040 $107,225,041 $189.77
81 66821 YAG Laser Capsulotomy After Cataract Surgery 490,106 1,364,008 $257,421,424 $188.72
174 93925 Complete Duplex Ultrasound of Leg Arteries, Both Legs 544,395 651,671 $119,635,797 $183.58
15 99285 Emergency Department Visit, Level 5 5,631,413 9,200,272 $1,648,406,729 $179.17
228 90792 Psychiatric Diagnostic Evaluation with Medical Assessment 450,696 518,792 $90,501,069 $174.45
448 90868 Transcranial Magnetic Stimulation, Follow-Up Treatment Session 7,954 224,796 $38,961,970 $173.32
132 70553 MRI Brain, With and Without Contrast 802,634 996,456 $170,620,203 $171.23
12 99215 Established Patient Office Visit, Level 5 5,937,739 10,896,507 $1,854,031,412 $170.15
443 72158 Low-Back MRI, Before and After Contrast 202,288 232,238 $39,507,617 $170.12
368 77263 Complex Radiation Therapy Treatment Planning 262,429 283,646 $48,200,786 $169.93
112 99306 Initial Nursing Facility Visit, High Level 866,247 1,182,905 $197,376,507 $166.86
71 43239 Upper GI Endoscopy (EGD) with Biopsy 1,195,212 1,746,756 $291,436,824 $166.84
441 95816 EEG, Awake and Drowsy 214,392 237,507 $39,581,595 $166.65
507 00300 Anesthesia for Head, Neck and Back Soft Tissue Surgery 134,415 205,721 $34,182,729 $166.16
497 93975 Complete Duplex Ultrasound of Abdominal and Pelvic Vessels 183,945 212,535 $35,035,589 $164.85
252 99350 Home Visit, Established Patient, Level 4 164,230 494,806 $81,144,436 $163.99
168 17004 Destruction of Fifteen or More Precancerous Skin Lesions 553,241 821,009 $134,528,569 $163.86
10 99204 New Patient Office Visit, Level 4 9,109,140 11,932,791 $1,943,604,414 $162.88
428 01922 Anesthesia for Imaging or Radiation Therapy 166,649 259,840 $41,188,190 $158.51
184 90791 Psychiatric Diagnostic Evaluation 636,387 712,066 $110,901,428 $155.75
414 17262 Destruction of Skin Cancer on Trunk, Arm, or Leg (Mid-Size) 222,774 283,359 $43,268,709 $152.70
72 92004 Comprehensive Eye Exam, New Patient 1,866,597 1,941,061 $290,217,690 $149.51
449 93978 Complete Duplex Ultrasound of Aorta, Vena Cava, and Iliac Vessels 227,154 259,795 $38,777,729 $149.26
391 27096 Sacroiliac Joint Injection with Imaging Guidance 219,433 306,189 $45,550,390 $148.77
90 96413 Chemotherapy Infusion, First Hour 239,411 1,689,792 $246,861,057 $146.09
307 68761 Punctal Plug Insertion for Dry Eye 178,656 422,453 $61,576,860 $145.76
459 31500 — 230,166 260,208 $37,549,093 $144.30
407 43235 Upper GI Endoscopy, Diagnostic 247,870 307,286 $44,015,577 $143.24
452 01480 Anesthesia for Lower Leg, Ankle and Foot Surgery 170,076 271,369 $38,381,202 $141.44
216 73721 MRI of Leg Joint, No Contrast 556,227 692,186 $96,234,873 $139.03
282 73221 Arm Joint MRI, No Contrast Dye 407,370 499,643 $69,461,707 $139.02
29 99222 Initial Hospital Care, Level 2 2,660,529 5,121,147 $695,505,461 $135.81
553 11602 Excision of Skin Cancer on Trunk, Arm, or Leg (Mid-Size) 191,705 224,302 $30,042,714 $133.94
237 00813 Anesthesia for Combined Upper and Lower Endoscopy 505,896 651,146 $86,348,582 $132.61
189 99305 Initial Nursing Facility Visit, Moderate Level 655,215 852,876 $110,110,893 $129.11
122 72148 MRI Lumbar Spine, without Contrast 1,234,644 1,416,914 $182,177,892 $128.57
92 93880 Carotid Duplex Ultrasound, Complete 1,689,833 1,857,479 $238,155,926 $128.21
28 90837 Psychotherapy, 60 Minutes 486,397 6,036,882 $769,967,259 $127.54
18 92014 Comprehensive Eye Exam, Established Patient 7,849,451 9,704,013 $1,237,170,993 $127.49
103 99310 Subsequent Nursing Facility Visit, Level 4 597,314 1,717,253 $212,763,626 $123.90
1 99214 Established Patient Office Visit, Level 4 25,344,649 97,520,328 $11,978,060,752 $122.83
51 67028 Intravitreal Injection of Medication 656,756 3,449,808 $423,604,328 $122.79
455 00400 Anesthesia for Skin Surgery on Limbs and Trunk 194,976 312,509 $37,858,549 $121.14
44 99284 Emergency Department Visit, Level 4 3,010,150 4,022,722 $486,941,768 $121.05
387 64636 Lower Back Facet Nerve Ablation, Additional Joint 177,675 378,025 $45,612,365 $120.66
164 99349 Home Visit, Established Patient, Level 3 298,248 1,140,992 $136,904,347 $119.99
23 93306 Transthoracic Echocardiogram, Complete with Doppler 5,952,942 6,836,435 $819,675,278 $119.90
271 72141 Neck MRI, No Contrast Dye 539,495 606,249 $72,343,712 $119.33
433 92235 Fluorescein Angiography of the Retina 268,252 338,900 $40,426,438 $119.29
450 10060 Incision and Drainage of Abscess, Simple 261,679 298,094 $35,388,284 $118.72
295 31575 Flexible Laryngoscopy, Diagnostic 427,692 546,566 $64,606,842 $118.21
527 01992 — 141,330 278,765 $32,823,099 $117.74
56 74177 CT Abdomen and Pelvis, With Contrast 2,509,907 3,437,874 $403,537,398 $117.38
397 11104 Punch Biopsy of Skin 306,965 330,333 $38,054,178 $115.20
462 11730 — 237,243 326,649 $37,400,606 $114.50
138 00731 Anesthesia for Upper GI Endoscopy 924,431 1,433,978 $160,624,570 $112.01
445 93312 Transesophageal Heart Ultrasound, Complete Service 263,365 310,451 $34,282,084 $110.43
315 99292 Critical Care, Additional Time 261,320 544,832 $59,920,850 $109.98
14 99203 New Patient Office Visit, Level 3 8,097,658 10,013,803 $1,080,462,481 $107.90
511 99183 Physician Supervision of Hyperbaric Oxygen Therapy 12,840 316,553 $34,093,600 $107.70
157 00811 Anesthesia for Diagnostic or Therapeutic Colonoscopy 1,031,067 1,335,306 $142,669,287 $106.84
544 72146 Mid-Back MRI, No Contrast Dye 207,632 233,160 $24,904,967 $106.81
77 17110 Destruction of Benign Lesions, Up to 14 1,987,531 2,645,161 $281,208,287 $106.31
46 99239 Hospital Discharge Day Management, Longer Visit 3,067,079 4,530,094 $478,678,675 $105.67
6 99233 Subsequent Hospital Care, Level 3 3,315,391 25,412,366 $2,634,498,730 $103.67
211 20611 Major Joint Injection or Aspiration with Ultrasound 467,421 947,470 $98,070,593 $103.51
120 00142 Anesthesia for Cataract and Lens Surgery 938,199 1,853,878 $188,759,773 $101.82
142 97161 Physical Therapy Evaluation, Low Complexity 1,281,553 1,456,942 $148,312,130 $101.80
158 97162 Physical Therapy Evaluation, Moderate Complexity 1,136,253 1,277,769 $129,792,349 $101.58
170 70551 Brain MRI Without Contrast 1,000,573 1,116,424 $113,402,185 $101.58
476 97163 Physical Therapy Evaluation, High Complexity 251,062 272,867 $27,671,466 $101.41
161 99221 Initial Hospital Care, Level 1 1,037,464 1,394,798 $139,111,996 $99.74
521 96133 Neuropsychological Test Interpretation, Extra Time 117,491 332,193 $33,091,885 $99.62
109 74176 CT Abdomen and Pelvis, Without Contrast 1,618,629 2,063,989 $201,851,261 $97.80
518 00910 Anesthesia for Transurethral Bladder Procedures 202,981 340,127 $33,222,069 $97.68
383 99316 Nursing Facility Discharge Visit, Longer Session 320,602 353,273 $34,460,399 $97.55
436 64494 Lower Back Facet Joint Injection, Second Level 268,269 414,404 $40,081,097 $96.72
137 93970 Complete Duplex Ultrasound of Limb Veins 1,315,054 1,582,625 $152,453,928 $96.33
143 71275 CT Angiogram of the Chest 1,278,618 1,492,818 $142,560,304 $95.50
255 95886 Complete Needle EMG of One Limb 489,245 845,333 $80,606,916 $95.36
350 76641 Complete Breast Ultrasound 382,800 533,100 $50,779,460 $95.25
572 70544 — 189,226 203,016 $19,051,837 $93.84
394 93923 Complete Arterial Circulation Study, Arms or Legs 311,934 370,570 $34,356,573 $92.71
60 92012 Established Patient Eye Exam, Intermediate Level 2,444,284 4,186,889 $387,115,030 $92.46
242 88307 Surgical Pathology Exam, Level V 539,262 933,515 $85,683,975 $91.79
278 70496 CT Angiogram of the Head 546,086 606,102 $55,594,230 $91.72
361 77002 Fluoroscopic Guidance for Needle Placement 286,091 546,872 $49,478,586 $90.48
468 99304 Initial Nursing Facility Visit, Level 1 255,349 285,561 $25,823,678 $90.43
356 76830 Transvaginal Pelvic Ultrasound 353,333 408,150 $36,772,695 $90.10
73 11102 Skin Biopsy, Tangential 2,500,281 3,164,738 $285,035,244 $90.07
61 90834 Psychotherapy, 45 Minutes 476,680 4,150,371 $371,826,422 $89.59
439 90836 Mid-Length Psychotherapy Session Added to a Medical Visit 82,389 448,021 $39,959,134 $89.19
270 70498 CT Angiogram of the Neck 570,437 628,491 $55,691,239 $88.61
515 70491 CT Scan of Neck Soft Tissue with Contrast 224,928 279,858 $24,783,126 $88.56
128 11042 Debridement, Subcutaneous Tissue 471,742 1,983,072 $175,482,914 $88.49
532 64484 — 214,866 338,925 $29,966,197 $88.42
516 88173 Fine Needle Aspiration Interpretation 224,241 330,091 $29,170,359 $88.37
275 77066 Diagnostic Mammogram, Both Breasts 549,830 580,441 $51,283,079 $88.35
2 99213 Established Patient Office Visit, Level 3 22,887,157 75,821,721 $6,576,266,392 $86.73
291 00812 Anesthesia for Screening Colonoscopy 501,323 628,788 $54,158,642 $86.13
378 36556 Non-Tunneled Central Line Placement, Age 5 and Over 324,553 388,157 $33,064,276 $85.18
25 99309 Subsequent Nursing Facility Visit, Level 3 1,594,140 9,866,536 $840,432,443 $85.18
559 78306 — 194,721 230,061 $19,310,894 $83.94
314 96401 Chemotherapy Injection Under the Skin or into Muscle 135,552 733,739 $60,207,747 $82.06
405 99348 Home Visit, Established Patient, Level 2 203,581 541,867 $44,315,500 $81.78
364 76856 Complete Pelvic Ultrasound, Non-Pregnancy 336,266 392,445 $31,687,391 $80.74
101 99497 Advance Care Planning Discussion 1,737,910 2,058,123 $165,943,023 $80.63
150 11056 Paring of Corns or Calluses, 2-4 Lesions 733,424 1,807,526 $145,665,378 $80.59
222 76700 Abdominal Ultrasound, Complete 726,355 833,218 $65,821,143 $79.00
375 71271 Low-Dose CT Lung Cancer Screening 326,725 344,064 $26,235,486 $76.25
508 92507 One-on-One Speech and Language Therapy 34,914 448,939 $34,142,952 $76.05
329 97597 Selective Wound Debridement, Smaller Area 252,533 745,720 $55,999,095 $75.09
194 88312 Special Stain for Microorganisms 729,442 1,444,658 $107,129,721 $74.16
196 76536 Ultrasound of Neck and Head Soft Tissues 817,361 935,186 $69,244,964 $74.04
322 90935 Hemodialysis Session with One Physician Evaluation 161,687 796,302 $58,374,786 $73.31
213 96365 Initial IV Infusion, Up to One Hour 305,195 1,336,145 $97,722,003 $73.14
546 88331 — 205,501 370,623 $27,059,695 $73.01
4 99232 Subsequent Hospital Care, Level 2 3,789,113 37,215,027 $2,669,892,525 $71.74
127 99238 Hospital Discharge Day Management, 30 Minutes or Less 1,413,958 1,778,858 $127,270,905 $71.55
97 71250 CT Scan of the Chest, No Contrast 1,769,318 2,257,052 $160,053,250 $70.91
117 99283 Emergency Department Visit, Level 3 1,537,243 1,962,482 $138,641,881 $70.65
27 77067 Screening Mammography, Bilateral 5,752,620 6,051,811 $423,514,524 $69.98
382 87801 Multi-Organism Molecular Screen 210,765 668,373 $46,559,010 $69.66
388 97164 Physical Therapy Re-evaluation 314,452 503,901 $35,018,653 $69.50
110 99202 New Patient Office Visit, Level 2 1,621,164 1,683,569 $116,095,625 $68.96
264 77065 Diagnostic Mammogram, One Breast 596,214 741,547 $50,410,599 $67.98
339 11055 Paring of a Single Corn or Callus 405,589 774,456 $52,481,678 $67.77
140 71260 CT Scan of the Chest with Contrast 1,301,973 1,849,987 $125,106,710 $67.63
195 93015 Cardiovascular Stress Test, Complete 830,301 851,352 $57,112,940 $67.08
152 90832 Individual Psychotherapy, 30 Minutes 386,090 2,183,758 $145,597,187 $66.67
31 99308 Subsequent Nursing Facility Visit, Level 2 1,550,824 10,209,627 $677,436,378 $66.35
230 90833 Shorter Psychotherapy Session Added to a Medical Visit 339,454 1,364,192 $89,967,109 $65.95
63 20610 Major Joint Injection or Aspiration 2,528,663 4,996,951 $325,715,460 $65.18
305 99454 Remote Monitoring Device Supply, 30 Days 181,082 959,345 $62,367,517 $65.01
328 70486 CT Scan of Sinuses and Facial Bones 429,649 466,492 $30,306,160 $64.97
400 73700 CT Scan of Leg or Foot, No Contrast 303,870 348,821 $22,534,025 $64.60
76 92083 Extended Visual Field Test 2,309,306 2,703,658 $169,698,387 $62.77
159 76770 Complete Retroperitoneal Ultrasound 1,116,646 1,299,410 $81,053,680 $62.38
541 86480 Tuberculosis Interferon-Gamma Blood Test 209,156 221,042 $13,652,027 $61.76
149 80307 Presumptive Drug Screen by Analyzer 917,248 2,380,998 $146,669,429 $61.60
447 88360 Manual Scoring of Tumor Immunostain 262,618 625,396 $38,272,716 $61.20
319 72131 CT Scan of the Lower (Lumbar) Spine, No Contrast 452,259 500,427 $29,857,229 $59.66
121 88342 Immunohistochemistry Stain, First Antibody 1,505,392 2,345,667 $139,376,391 $59.42
290 93922 Limited Arterial Circulation Study, Arms or Legs 508,764 621,881 $35,216,702 $56.63
146 93971 Limited or One-Sided Duplex Ultrasound of Limb Veins 1,260,268 1,613,776 $88,463,603 $54.82
360 98942 Chiropractic Spinal Manipulation, Five Regions 103,450 939,102 $49,746,958 $52.97
266 76642 Limited Breast Ultrasound 593,238 721,907 $38,222,569 $52.95
26 99212 Established Patient Office Visit, Level 2 5,874,703 9,445,828 $499,353,610 $52.86
371 99457 Remote Monitoring Management, First 20 Minutes 189,816 929,420 $48,047,643 $51.70
160 72125 CT Scan of the Neck (Cervical) Spine, No Contrast 1,109,391 1,302,084 $66,917,199 $51.39
231 87635 COVID-19 PCR Test 694,634 884,590 $45,198,325 $51.10
206 11103 Additional Shave-Style Skin Biopsy 791,568 1,387,434 $70,879,814 $51.09
21 88305 Surgical Pathology Exam, Level IV 7,117,669 18,464,904 $940,253,610 $50.92
40 17000 Destruction of Premalignant Skin Lesion, First 3,860,382 5,622,387 $285,409,736 $50.76
488 64447 Femoral Nerve Block, Single Injection 242,928 279,964 $14,209,403 $50.75
299 20550 Tendon Sheath, Ligament, or Fascia Injection 492,136 780,892 $39,558,009 $50.66
442 20605 Intermediate Joint Injection or Aspiration 266,268 374,146 $18,733,939 $50.07
565 20552 Trigger Point Injection, One or Two Muscles 189,962 296,975 $13,985,537 $47.09
457 20600 Arthrocentesis, Small Joint 257,984 393,692 $18,326,119 $46.55
302 36620 Arterial Line Placement, Percutaneous 488,528 549,249 $24,751,481 $45.06
83 11721 Trimming of Six or More Thickened Nails 2,148,870 5,698,240 $255,652,994 $44.87
162 69210 Impacted Earwax Removal, Instrumentation 1,081,715 1,423,753 $63,560,186 $44.64
340 77300 Basic Radiation Dose Calculation 261,168 1,216,572 $53,750,894 $44.18
52 70450 CT Head/Brain, without Contrast 3,324,590 5,014,709 $218,882,950 $43.65
334 76775 Limited Retroperitoneal Ultrasound 416,894 472,823 $20,520,678 $43.40
245 99307 Subsequent Nursing Facility Visit, Level 1 600,276 1,920,893 $82,841,944 $43.13
259 88313 Special Stain for Tissue Elements and Pigments 605,941 1,529,684 $65,617,716 $42.90
487 99282 — 245,305 286,881 $12,014,024 $41.88
510 87811 Rapid COVID-19 Antigen Test 225,499 287,108 $11,742,904 $40.90
269 88112 Non-Gynecologic Enhanced Cytology 572,919 859,273 $35,074,103 $40.82
186 76942 Ultrasound Guidance for Needle Placement 880,395 1,126,070 $45,900,154 $40.76
50 92134 Retinal OCT Scan 3,347,070 7,443,630 $302,794,297 $40.68
163 92136 Eye Measurement for Cataract Lens Power 1,076,672 1,779,205 $72,366,541 $40.67
125 99490 Chronic Care Management, First 20 Minutes 886,895 4,476,813 $181,035,221 $40.44
513 76882 Limited Ultrasound of an Arm or Leg 225,058 290,578 $11,651,089 $40.10
42 98941 Chiropractic Spinal Manipulation, Three to Four Regions 1,299,804 12,779,547 $508,323,056 $39.78
165 92557 Comprehensive Audiometry 1,067,782 1,145,329 $45,084,963 $39.36
179 76705 Limited Abdominal Ultrasound 886,914 1,036,220 $40,757,015 $39.33
268 83880 Natriuretic Peptide (BNP or NT-proBNP) Blood Test 589,890 865,023 $33,877,142 $39.16
62 92250 Retinal Photography with Interpretation 2,852,757 3,356,228 $130,791,509 $38.97
116 99231 Subsequent Hospital Care, Level 1 1,374,811 5,009,819 $188,979,702 $37.72
32 77063 Screening 3D Breast Tomosynthesis, Both Breasts 5,013,185 5,279,199 $198,619,990 $37.62
193 94729 Gas Diffusing Capacity Test (DLCO) 852,447 924,886 $34,619,327 $37.43
74 92133 Optic Nerve Imaging (OCT) 2,342,050 2,667,742 $95,554,814 $35.82
24 97530 Therapeutic Activities, Per 15 Minutes 1,467,188 23,942,717 $853,000,668 $35.63
466 94727 Lung Volume Testing by Gas Dilution or Washout 255,601 272,313 $9,690,127 $35.58
524 92025 Computerized Corneal Mapping (Topography) 218,275 255,324 $9,027,735 $35.36
422 87150 Organism Identification by Amplified Nucleic Acid Probe 76,731 1,192,595 $41,793,163 $35.04
390 87640 Staphylococcus Aureus DNA Test 314,353 511,897 $17,937,593 $35.04
107 87798 Molecular Test for an Unlisted Organism 454,322 5,985,470 $209,654,039 $35.03
530 87500 Vancomycin Resistance Gene Test 216,725 332,704 $11,646,231 $35.00
500 87624 High-Risk HPV DNA Test 230,873 238,266 $8,338,151 $35.00
552 87651 Group A Strep Molecular Test 202,037 310,385 $10,852,153 $34.96
549 95251 Continuous Glucose Monitor Data Interpretation 204,399 440,802 $15,168,523 $34.41
281 94726 Lung Volume Testing by Body Plethysmography 539,549 576,876 $19,671,372 $34.10
210 11720 Nail Trimming/Debridement, Up to 5 766,106 1,879,960 $63,444,804 $33.75
234 94060 Spirometry, Pre- and Post-Bronchodilator 688,201 774,649 $26,100,521 $33.69
381 72050 Neck (Cervical) Spine X-ray, Extended Views 320,725 358,464 $11,938,231 $33.30
153 73564 Complete Knee X-Ray, Four or More Views 1,178,428 1,610,328 $53,597,198 $33.28
226 72110 Lower Back (Lumbar) Spine X-ray, Full Series 720,956 809,529 $26,792,021 $33.10
453 74230 Swallowing Study with Video X-ray 261,143 301,549 $9,851,692 $32.67
342 93308 Limited or Follow-Up Heart Ultrasound 398,817 493,166 $16,064,239 $32.57
475 96367 — 127,815 1,145,812 $36,671,041 $32.00
379 97113 Aquatic Therapy with Exercise 48,160 1,526,844 $47,241,044 $30.94
33 97112 Neuromuscular Re-education Therapy 1,548,700 21,724,110 $666,416,166 $30.68
36 82306 Vitamin D, 25-Hydroxy 4,764,939 6,460,399 $190,852,163 $29.54
238 92020 Gonioscopy, Exam of the Eye's Drainage Angle 668,740 766,833 $22,378,398 $29.18
265 97535 Self-Care and Home Management Training 454,632 2,628,412 $74,506,042 $28.35
114 73562 Knee X-Ray, Three Views 1,545,180 2,244,980 $63,315,205 $28.20
173 98940 Chiropractic Spinal Manipulation, One to Two Regions 609,085 4,516,164 $126,698,538 $28.05
496 82670 Estradiol Blood Test 235,089 364,301 $10,148,223 $27.86
91 73502 Hip X-Ray, Two or Three Views 1,860,966 2,583,712 $69,088,371 $26.74
373 92201 Extended Retinal Exam with Drawing, Peripheral Retina 327,659 461,224 $12,208,425 $26.47
418 93320 Full Doppler Flow Measurement with Heart Ultrasound 288,017 319,184 $8,438,480 $26.44
528 93228 Mobile Cardiac Telemetry, Physician Review and Report 217,081 222,546 $5,827,222 $26.18
224 84403 Total Testosterone Blood Test 724,114 1,176,931 $30,265,473 $25.72
484 84402 Free Testosterone Blood Test 246,056 376,546 $9,563,354 $25.40
438 73140 Finger X-Ray 268,525 365,524 $9,229,585 $25.25
17 97110 Therapeutic Exercise, 15 Minutes 2,696,626 58,723,464 $1,481,216,120 $25.22
519 77001 — 221,604 270,197 $6,734,522 $24.92
240 73110 Full Wrist X-Ray Series 658,583 1,041,387 $25,897,070 $24.87
131 72100 Lower Back (Lumbar) Spine X-ray, Limited Views 1,395,972 1,745,606 $43,217,367 $24.76
108 73630 Foot X-ray, Complete Series 1,641,895 2,614,098 $64,419,999 $24.64
372 88185 Flow Cytometry, Additional Marker, Technical Work 87,810 1,957,364 $47,904,554 $24.47
301 72040 Neck (Cervical) Spine X-ray, Limited Views 489,510 614,726 $15,024,857 $24.44
244 97116 Gait Training Therapy 299,659 3,518,858 $85,471,881 $24.29
551 93356 Heart Muscle Strain Imaging Add-On 202,102 217,785 $5,277,549 $24.23
261 94010 Spirometry 601,381 783,787 $18,626,181 $23.76
191 73130 Full Hand X-Ray Series 867,858 1,256,440 $28,786,191 $22.91
204 73610 Full Ankle X-Ray Series 791,652 1,205,466 $27,382,218 $22.72
69 77080 DEXA Bone Density, Axial 2,641,947 2,761,058 $62,670,197 $22.70
93 73030 Shoulder X-ray, Complete 1,855,590 2,661,360 $59,739,443 $22.45
35 97140 Manual Therapy, 15 Minutes 1,985,892 27,788,079 $622,866,656 $22.41
522 83861 — 218,823 590,291 $13,231,276 $22.41
385 92285 External Photography of the Eye and Lids 319,292 394,973 $8,657,661 $21.92
199 93016 Cardiac Stress Test, Supervision Only 810,073 827,784 $17,916,121 $21.64
386 73620 Foot X-ray, Two Views 318,547 469,330 $10,146,257 $21.62
569 84270 Sex Hormone Binding Globulin Blood Test 189,641 322,904 $6,979,618 $21.62
84 99211 Established Patient Office Visit, Minimal 2,084,155 3,651,655 $78,707,873 $21.55
474 71101 Rib X-ray, One Side, with Chest View 251,294 280,839 $5,874,942 $20.92
308 86334 Serum Immunofixation Electrophoresis 475,359 836,561 $17,362,266 $20.75
169 73560 Basic Knee X-Ray, One or Two Views 1,025,084 1,492,020 $30,618,601 $20.52
227 88304 Surgical Pathology Exam, Level III 711,799 858,221 $17,558,959 $20.46
463 72070 Mid-Back (Thoracic) Spine X-ray, Two Views 256,513 300,670 $6,118,973 $20.35
504 82378 — 227,843 509,584 $9,636,509 $18.91
495 93227 — 237,317 248,957 $4,664,949 $18.74
561 73501 — 193,026 239,715 $4,453,857 $18.58
351 84154 Free PSA Blood Test 366,328 453,415 $8,323,537 $18.36
82 84153 Prostate-Specific Antigen (PSA), Total 2,184,511 3,181,936 $58,378,719 $18.35
554 83090 Homocysteine Blood Test 199,746 254,770 $4,562,031 $17.91
392 73080 Full Elbow X-Ray Series 312,256 394,213 $7,028,767 $17.83
454 86235 Extractable Nuclear Antigen Antibody 260,119 1,574,250 $28,056,880 $17.82
377 83520 Quantitative Immunoassay, Substance Not Otherwise Specified 325,016 790,019 $13,593,766 $17.21
294 76937 Ultrasound Guidance for Vascular Access 497,427 643,289 $11,040,088 $17.16
34 71046 Chest X-ray, Two Views 4,865,680 6,785,593 $115,098,098 $16.96
171 84481 Free Triiodothyronine (T3) Blood Test 966,469 1,433,993 $24,225,491 $16.89
306 92202 Extended Eye Exam with Drawing, Optic Nerve and Macula 475,579 715,768 $12,080,094 $16.88
11 84443 Thyroid-Stimulating Hormone (TSH) 9,350,590 14,142,754 $237,311,904 $16.78
212 92567 Eardrum Movement Test (Tympanometry) 764,413 840,782 $14,014,786 $16.67
413 87804 Rapid Influenza Antigen Test 289,853 566,139 $9,299,760 $16.43
430 87880 Rapid Strep A Antigen Test 278,704 308,259 $5,047,947 $16.38
492 86800 Thyroglobulin Antibody 241,240 310,555 $4,931,405 $15.88
456 74019 Abdominal X-ray, Two Views 259,172 331,866 $5,264,083 $15.86
477 90471 Immunization Administration, First 250,992 261,660 $4,149,584 $15.86
419 82274 Fecal Immunochemical Test for Blood 287,891 308,257 $4,884,141 $15.84
352 73552 Thigh Bone X-Ray 364,487 529,908 $8,302,782 $15.67
202 95165 Preparation of Allergy Immunotherapy Extracts 174,585 6,638,011 $102,244,712 $15.40
22 93000 Electrocardiogram (ECG), Complete 6,791,421 10,271,035 $155,781,713 $15.17
490 73060 Upper Arm Bone X-Ray 241,856 328,764 $4,956,598 $15.08
54 82607 Vitamin B12 Level 3,091,224 4,120,819 $62,019,191 $15.05
545 97150 Group Therapy Session 206,154 1,525,393 $22,418,968 $14.70
106 82746 Serum Folate Blood Test 1,699,907 2,241,268 $32,895,184 $14.68
172 93018 Cardiac Stress Test, Interpretation and Report Only 965,933 988,514 $14,430,738 $14.60
248 72170 Basic Pelvis X-Ray 632,526 730,576 $10,616,509 $14.53
363 86376 Thyroid Microsomal Antibody 338,549 412,422 $5,988,888 $14.52
473 99406 Smoking Cessation Counseling, Intermediate 251,357 388,981 $5,590,415 $14.37
217 84165 Serum Protein Electrophoresis (SPEP) 740,453 1,246,358 $17,842,839 $14.32
297 86803 Hepatitis C Antibody Test 495,966 538,757 $7,662,008 $14.22
325 84480 Total Triiodothyronine (T3) Blood Test 442,322 626,521 $8,870,604 $14.16
354 73590 Lower Leg X-Ray 356,189 473,353 $6,613,034 $13.97
502 86225 Double-Stranded DNA Antibody 229,279 281,330 $3,847,325 $13.68
80 96372 Therapeutic or Diagnostic Injection (SubQ/IM) 2,217,960 7,870,235 $107,263,624 $13.63
324 88311 Decalcification of Tissue for Sectioning 442,957 579,940 $7,892,400 $13.61
96 82728 Ferritin Blood Test 1,792,841 3,048,255 $41,445,947 $13.60
9 80061 Lipid Panel 11,874,207 17,828,953 $238,202,166 $13.36
367 86141 High-Sensitivity C-Reactive Protein 331,907 447,835 $5,790,608 $12.93
421 86200 Cyclic Citrullinated Peptide Antibody 284,813 313,295 $4,037,892 $12.89
539 84466 Transferrin Blood Test 210,067 353,744 $4,497,344 $12.71
471 76376 3D Image Reconstruction and Interpretation 253,230 289,927 $3,680,379 $12.69
435 80305 Presumptive Drug Screen, Visually Read 270,595 598,438 $7,430,256 $12.42
254 86038 Antinuclear Antibody Screen 625,164 716,694 $8,646,154 $12.06
155 74018 Abdominal X-ray, Single View 1,171,003 2,072,588 $24,737,595 $11.94
380 83516 — 321,726 667,074 $7,667,721 $11.49
526 97035 — 217,762 1,485,077 $16,954,481 $11.42
337 76514 Corneal Thickness Measurement by Ultrasound 412,924 443,114 $4,972,419 $11.22
427 51741 Complex Urine Flow Study 280,848 357,469 $3,966,786 $11.10
482 11719 — 247,293 648,208 $7,078,892 $10.92
144 51798 Post-Void Residual Urine, Ultrasound 1,270,548 1,905,290 $20,090,624 $10.54
5 80053 Comprehensive Metabolic Panel 13,529,894 27,383,096 $288,548,774 $10.54
304 83721 Direct LDL Cholesterol Measurement 477,997 673,077 $7,049,545 $10.47
464 87340 Hepatitis B Surface Antigen Test 255,806 277,376 $2,854,586 $10.29
16 83036 Hemoglobin A1c 7,947,832 14,058,139 $136,052,308 $9.68
30 71045 Chest X-ray, Single View 5,579,275 15,025,724 $142,186,524 $9.46
45 84439 Free Thyroxine (Free T4) 3,470,611 5,220,321 $46,989,247 $9.00
509 93321 Focused Doppler Flow Measurement with Heart Ultrasound 226,199 272,961 $2,430,803 $8.91
119 83550 Iron Binding Capacity Blood Test 1,524,243 2,463,689 $21,478,396 $8.72
288 80069 Renal Function Panel 518,517 1,001,794 $8,665,532 $8.65
129 87186 Antibiotic Susceptibility Panel, MIC 1,412,108 2,501,120 $21,612,455 $8.64
331 87070 Bacterial Culture, Other Source 425,106 529,582 $4,559,348 $8.61
48 80048 Basic Metabolic Panel 3,371,149 5,770,979 $48,700,704 $8.44
20 93010 Electrocardiogram (ECG), Interpretation Only 7,378,908 16,114,564 $135,929,483 $8.44
201 80076 Liver Function Blood Panel 798,605 1,264,603 $10,293,590 $8.14
135 87088 Urine Culture with Isolate Identification 1,336,346 2,061,088 $16,655,452 $8.08
151 87077 Definitive Identification of Cultured Isolate 1,197,223 1,877,205 $15,144,661 $8.07
68 87086 Urine Culture, Quantitative 2,652,759 4,367,506 $35,202,501 $8.06
8 85025 Complete Blood Count with Differential 12,316,906 26,924,736 $208,693,012 $7.75
555 93042 — 197,947 310,513 $2,220,336 $7.15
369 82977 Gamma-Glutamyl Transferase (GGT) Blood Test 331,141 532,939 $3,809,317 $7.15
359 83690 Lipase Blood Test 342,801 430,709 $2,959,366 $6.87
209 84436 Total Thyroxine (T4) Blood Test 775,304 1,042,488 $7,154,891 $6.86
100 83735 Magnesium Blood Level 1,753,788 3,260,800 $21,783,672 $6.68
296 93325 Color Flow Mapping with Heart Ultrasound 497,018 595,977 $3,935,343 $6.60
181 82550 Total Creatine Kinase Blood Test 886,367 1,417,475 $9,199,408 $6.49
424 82150 Amylase Blood Test 283,739 381,873 $2,468,260 $6.46
333 84479 Thyroid Hormone Uptake Test 418,646 563,653 $3,642,820 $6.46
78 85027 Complete Blood Count, Automated, No Differential 2,222,466 3,274,253 $21,137,646 $6.46
89 83540 Serum Iron Level 1,868,107 3,121,903 $20,147,026 $6.45
353 93005 Electrocardiogram, Tracing Only 363,903 416,476 $2,676,032 $6.43
59 17003 Destruction of Additional Precancerous Skin Lesions 2,897,728 18,008,414 $112,348,324 $6.24
404 82044 — 298,985 379,181 $2,338,980 $6.17
253 83615 Lactate Dehydrogenase (LDH) Blood Test 625,499 1,450,030 $8,712,454 $6.01
416 85730 Partial Thromboplastin Time (PTT) Blood Test 289,338 369,612 $2,218,947 $6.00
64 82043 Urine Microalbumin, Quantitative 2,707,442 3,614,031 $20,821,831 $5.76
310 86431 Rheumatoid Factor, Quantitative 475,100 577,308 $3,267,295 $5.66
229 84460 ALT (Alanine Aminotransferase) Blood Test 705,974 1,740,875 $9,134,224 $5.25
57 82570 Creatinine, Non-Blood Sample 3,060,713 4,578,192 $23,649,140 $5.17
133 86140 C-Reactive Protein, Standard 1,338,482 2,306,059 $11,911,981 $5.17
273 84450 AST (Aspartate Aminotransferase) Blood Test 552,775 850,268 $4,316,554 $5.08
183 82565 Creatinine, Blood 883,253 1,333,510 $6,706,088 $5.03
410 84075 Total Alkaline Phosphatase Blood Test 295,000 418,946 $2,092,458 $4.99
235 82248 Direct Bilirubin Blood Test 672,824 1,034,529 $5,116,390 $4.95
444 82247 Total Bilirubin Blood Test 265,815 434,294 $2,106,464 $4.85
345 82310 Total Calcium Blood Test 395,590 553,812 $2,685,951 $4.85
358 82040 Blood Albumin Test 344,832 511,308 $2,453,974 $4.80
425 96127 Brief Emotional/Behavioral Screening, Per Instrument 281,588 497,719 $2,386,084 $4.79
431 84132 Potassium Blood Level 277,390 411,448 $1,946,409 $4.73
188 84100 Phosphorus (Inorganic Phosphate) Blood Test 875,557 1,711,362 $8,070,794 $4.72
535 84295 — 213,902 317,680 $1,456,396 $4.58
105 84550 Uric Acid Blood Test 1,717,712 2,856,663 $12,873,351 $4.51
177 85610 Prothrombin Time (PT/INR) 919,579 5,241,264 $22,429,845 $4.28
556 86592 — 196,386 226,228 $965,630 $4.27
563 87205 — 191,918 243,325 $1,037,188 $4.26
347 85651 Erythrocyte Sedimentation Rate, Manual 386,375 630,838 $2,683,018 $4.25
493 95004 Skin Prick Allergy Testing 151,608 8,362,258 $35,232,964 $4.21
283 81000 Manual Urinalysis with Microscopy 535,756 891,020 $3,562,252 $4.00
499 85045 Automated Reticulocyte Count 231,623 322,586 $1,285,085 $3.98
286 82947 Glucose, Quantitative (Blood) 529,131 975,744 $3,808,667 $3.90
332 84520 Urea Nitrogen (BUN) 422,629 617,334 $2,389,338 $3.87
247 84156 Total Protein Measurement, Urine 632,537 1,111,099 $4,068,228 $3.66
326 84155 Total Protein, Blood 442,069 605,922 $2,169,343 $3.58
102 81002 Manual Urinalysis, Dipstick Only 1,723,102 2,589,054 $8,958,317 $3.46
316 82962 Blood Sugar Check with Handheld Glucose Meter 460,380 1,012,490 $3,295,379 $3.25
38 81001 Urinalysis, Automated with Microscopy 4,093,507 6,389,937 $20,203,552 $3.16
3 36415 Routine Venipuncture (Blood Draw) 15,860,566 42,365,821 $126,789,250 $2.99
139 85652 Erythrocyte Sedimentation Rate, Automated 1,310,799 2,168,461 $5,843,861 $2.69
505 85018 — 227,842 375,291 $884,727 $2.36
43 81003 Urinalysis, Automated without Microscopy 3,597,838 5,728,729 $12,831,695 $2.24

Beneficiary counts apply to one code at a time. A patient who received two of these codes is counted under both, so the column cannot be added up into a number of people. Rank is each code's position among all 7,889 CPT codes billed to Medicare in CY2021, so the column skips a number wherever a code we don't yet cover sits.

Which codes bring in the most Medicare money?

Spending concentrates hard. The top 25 codes carry 57.2% of the $82.1B these 500 codes account for.

  1. 1 99214 Established Patient Office Visit, Level 4 $12.0B
  2. 2 99213 Established Patient Office Visit, Level 3 $6.6B
  3. 3 99232 Subsequent Hospital Care, Level 2 $2.7B
  4. 4 99233 Subsequent Hospital Care, Level 3 $2.6B
  5. 5 66984 Cataract Surgery with Lens Implant $2.0B
  6. 6 99204 New Patient Office Visit, Level 4 $1.9B
  7. 7 99215 Established Patient Office Visit, Level 5 $1.9B
  8. 8 99223 Initial Hospital Care, Level 3 $1.8B
  9. 9 99285 Emergency Department Visit, Level 5 $1.6B
  10. 10 97110 Therapeutic Exercise, 15 Minutes $1.5B

Why the most common codes aren't the most expensive

Rank the same 500 codes by patients and then by dollars, and the two lists disagree. A cheap service given to millions and a costly one given to thousands can land far apart depending on which question you ask.

Many patients, little money
81003 Urinalysis, Automated without Microscopy
By beneficiaries
#28
By allowed dollars
#398
Per service
$2.24
Few patients, lots of money
37229 Below-Knee Artery Atherectomy, First Vessel
By beneficiaries
#469
By allowed dollars
#41
Per service
$8,085.48

What this data covers — and what it doesn't

These are CY2021 Medicare fee-for-service totals at the national level. Medicare Advantage, Medicaid and commercial volume are excluded, so real-world use of every code here runs higher than the numbers show.

Beneficiary counts belong to a single code. Summing that column would count the same patient once for every code they received, so this page never totals it or calls it a patient count.

The shortlist covers numeric CPT codes. Drug codes and HCPCS Level II are excluded by design — the first are billed per unit, which makes service counts incomparable, and the second already carry CMS-owned descriptions.

7 codes on this list have since left the fee schedule. CMS billed them heavily in CY2021 and then deleted them, so their links point at the last quarter that priced them rather than at a page that no longer exists.

How the ranking is built

A code's overall position is its best standing across two measures: unique beneficiaries served and total allowed dollars. Ranking on either one alone buries half the story — beneficiaries favor cheap high-volume tests, dollars favor expensive procedures. Sort the table by a single measure to see each view on its own. The ranking spans all 7,889 CPT codes billed to Medicare in CY2021; this table shows the top 500 we cover.

Source: CMS Medicare Physician & Other Practitioners — by Geography and Service, national rows, CY2021. This is a calendar-year snapshot on its own publication cycle, separate from the quarterly fee schedule that produces the rates on each code page. Full methodology.

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