Priced under CLFS
80048 · CLFS Q4 2026
National CLFS allowed amount · Q4 2026
$8.46
National lab fee-schedule amount, before sequestration. No locality adjustment applies to this amount.
No Physician Fee Schedule amount—priced under the Clinical Laboratory Fee Schedule.
View CLFS amount and evidenceAmount evidence: Clinical Laboratory Fee Schedule
Effective Jan 1, 2026 · Lab payment rules and source details
Inspect PFS status evidence
- Code
- 80048
- Release
- Q4 2026, revision 2
- Result
- Priced under CLFS
Citations
-
Shows this code’s PFS status (X). Result: Priced under CLFS.
Physician relative value file (PPRRVU)CMS RVU26DOctober 1 – December 31, 2026revision 2
This PFS record alone does not establish a $0 allowance or a coverage determination. Any amount from another schedule needs its own evidence.
PPRRVU2026_Oct_nonQPP.csv row 9,586 in rvu26d-updated-08-26-2026.zip
In the CMS file
Loading rows 9,584–9,588 of PPRRVU2026_Oct_nonQPP.csv…
Download rvu26d-updated-08-26-2026.zip from CMS File fingerprint
4d0d3f19bd954ffc0f5b8439169d267da023d4f6911f4539bb6e98723cb1a626
The national CLFS allowed amount is $8.46 for CPT 80048 under the Clinical Laboratory Fee Schedule (CLFS)—a single national rate, the same in every locality, before the ~2% sequestration cut. On the Physician Fee Schedule CPT 80048 carries status X (statutory exclusion) because lab services are paid under the CLFS instead. Figure from the Q4 2026 CLFS file, effective January 1, 2026.
Why is there no national PFS amount for 80048?
Its status indicator is X (statutory exclusion). The statutory definition of physician services does not include this item. The lab schedule supplies the pricing information shown above. See the CLFS evidence.
The Medicare lab fee for 80048 Copy link
Priced under the Clinical Laboratory Fee Schedule, not the Physician Fee Schedule
80048 carries status X on the Physician Fee Schedule because Medicare pays for clinical lab tests under a separate fee schedule, the CLFS. Since 2018 the CLFS rate is a single national amount—the same in every state and setting, with no locality adjustment.
Original Medicare generally pays 100% of the CLFS amount for covered clinical diagnostic lab tests—no Part B coinsurance or deductible, unlike most physician services.
National CLFS rate
$8.46
Q4 2026 CLFS file · effective Jan 1, 2026 · same with modifier QW
Before the ~2% sequestration cut applied at claim payment. Lab tests billed by a hospital outpatient department may be packaged into the facility payment instead.
This record establishes the published lab amount and its effective date. It does not establish patient-specific coverage or whether a claim is packaged into another payment.
Source fields and checksum
- Code
- 80048
- Modifier
- Blank
- Pricing indicator
- N
- Allowed amount
- $8.46
- Effective date
- 2026-01-01
- File SHA-256
- fcfec34526c443902747deae74339aae6f8bc79f26b3239cc017c278bf730e0e
Payment considerations Copy link
Here are the inputs and payment rules that apply to this code. Each link takes you to the detail below.
Other payment indicators (7)
Why would a Medicare claim for 80048 be denied or paid less?
These come from CMS indicators on this page, not general billing advice.
- Its status indicator is X (statutory exclusion)—The statutory definition of physician services does not include this item. Medicare prices this code under the Clinical Laboratory Fee Schedule instead; the CLFS rate is shown on this page. See CLFS rate
- 8 codes form NCCI pairs with 80048 carrying modifier indicator 0—no NCCI-associated modifier bypasses the edit, so billed together on the same date of service, a line of the pair denies. See billing together
- 9 codes pair with 80048 under modifier indicator 1—separately payable only when an NCCI-associated modifier (59, or a more specific XE, XS, XP, or XU) is clinically appropriate and the documentation supports a distinct service; without one, a line of the pair denies. See billing together
- More than 2 units per patient per date of service exceeds 80048's Medically Unlikely Edit (MUE) limit. See billing together
Payer-specific coverage and documentation rules live outside these files, so a claim that clears every check here can still be denied on other grounds.
What do commercial payers pay for 80048? Copy link
Negotiated rates for 80048 vs Medicare Copy link
Commercial payers' negotiated rates for 80048 have medians of 70% to 100% of Medicare, depending on specialty.
Insurers must publish the rates they negotiate with in-network clinicians (the Transparency in Coverage rule). We reduce each file to medians by county and specialty and set them against Medicare's amount for the same place.
BCBSIL PPO · Cook County, IL
Rate file of October 2026
Medicare (100%): $8.46, the CLFS Q4 2026 national lab limit in this county's payment locality.
-
Internal Medicine
2,961 providers · 1,067 groups
100% 100–104%
Median $8.46 · middle half $8.46–$8.76 · 67% of providers at exactly $8.46
-
Family Medicine
1,819 providers · 860 groups
100% 100–104%
Median $8.46 · middle half $8.46–$8.76 · 72% of providers at exactly $8.46
BCBSTX Blue Choice PPO · Harris County, TX
Rate file of October 2026
Medicare (100%): $8.46, the CLFS Q4 2026 national lab limit in this county's payment locality.
-
Internal Medicine
1,930 providers · 717 groups
70%
Median $5.92 · 97% of providers at exactly $5.92
Payers publish this data, and each dataset carries its month. A negotiated rate describes the contract, not the payment, and networks and plan designs vary. We publish a benchmark only when at least 10 providers from at least 5 separately contracting groups (tax IDs) stand behind it, and no single group accounts for more than 25% of it. Browse all payer benchmarks →
Which billing rules and modifiers apply? Copy link
Global period: what 80048's fee already covers Copy link
The global surgery concept does not apply to this code.
Can you bill it with another code? Copy link
Check a pair of codes Copy link
Enter a second CPT or HCPCS code billed on the same date of service. We'll check the current NCCI procedure-to-procedure edit for the pair.
Billing together (NCCI edits) Copy link
NCCI Q4 2026Based on CMS's National Correct Coding Initiative (NCCI). A few examples appear here; use the complete edit page to check a specific pair.
Not separately payable with 80048 on the same date of service—no modifier bypasses the edit (modifier indicator 0)
Showing 3 of 8.
Separately payable with 80048 only when an NCCI-associated modifier is appropriate and documented (modifier indicator 1)
Showing 3 of 9.
Modifier 59 and the X modifiers are not a universal bypass—CMS expects the most specific applicable modifier, and which one that is depends on the pair and the documented circumstances.
Check a paired code or view all 17 NCCI pairs →
Medically Unlikely Edit (MUE) limit: 2 units per patient per date of service.
How has it changed? Copy link
Rate history by release Copy link
National Office (non-facility) amount for 80048 across quarterly releases.
| Release | Status | Office | Facility |
|---|---|---|---|
| Q4 2026 Oct 1, 2026 – present | X | — | — |
| Q3 2026 Jul 1, 2026 – Sep 30, 2026 | X | — | — |
| Q2 2026 Apr 1, 2026 – Jun 30, 2026 | X | — | — |
| Q1 2026 Jan 1, 2026 – Mar 31, 2026 | X | — | — |
| Q4 2025 Oct 1, 2025 – Dec 31, 2025 | X | — | — |
| Q3 2025 Jul 1, 2025 – Sep 30, 2025 | X | — | — |
| Q2 2025 Apr 1, 2025 – Jun 30, 2025 | X | — | — |
| Q1 2025 Jan 1, 2025 – Mar 31, 2025 | X | — | — |
| Q4 2024 Oct 1, 2024 – Dec 31, 2024 | X | — | — |
| Q3 2024 Jul 1, 2024 – Sep 30, 2024 | X | — | — |
| Q2 2024 Apr 1, 2024 – Jun 30, 2024 | X | — | — |
| Q1 2024 Mar 9, 2024 – Mar 31, 2024 | X | — | — |
| Q1 2024 Jan 1, 2024 – Mar 8, 2024 | X | — | — |
| Q4 2023 Oct 1, 2023 – Dec 31, 2023 | X | — | — |
| Q3 2023 Jul 1, 2023 – Sep 30, 2023 | X | — | — |
| Q2 2023 Apr 1, 2023 – Jun 30, 2023 | X | — | — |
| Q1 2023 Jan 1, 2023 – Mar 31, 2023 | X | — | — |
| Q4 2022 Oct 1, 2022 – Dec 31, 2022 | X | — | — |
| Q3 2022 Jul 1, 2022 – Sep 30, 2022 | X | — | — |
| Q2 2022 Apr 1, 2022 – Jun 30, 2022 | X | — | — |
| Q1 2022 Jan 1, 2022 – Mar 31, 2022 | X | — | — |
| Q4 2021 Oct 1, 2021 – Dec 31, 2021 | X | — | — |
| Q3 2021 Jul 1, 2021 – Sep 30, 2021 | X | — | — |
| Q2 2021 Apr 1, 2021 – Jun 30, 2021 | X | — | — |
| Q1 2021 Jan 1, 2021 – Mar 31, 2021 | X | — | — |
| Q4 2020 Oct 1, 2020 – Dec 31, 2020 | X | — | — |
| Q3 2020 Jul 1, 2020 – Sep 30, 2020 | X | — | — |
| Q2 2020 Apr 1, 2020 – Jun 30, 2020 | X | — | — |
| Q1 2020 Jan 1, 2020 – Mar 31, 2020 | X | — | — |
| Q4 2019 Oct 1, 2019 – Dec 31, 2019 | X | — | — |
| Q3 2019 Jul 1, 2019 – Sep 30, 2019 | X | — | — |
| Q2 2019 Apr 1, 2019 – Jun 30, 2019 | X | — | — |
| Q1 2019 Jan 1, 2019 – Mar 31, 2019 | X | — | — |
| Q4 2018 Oct 1, 2018 – Dec 31, 2018 | X | — | — |
| Q3 2018 Jul 1, 2018 – Sep 30, 2018 | X | — | — |
| Q2 2018 Apr 1, 2018 – Jun 30, 2018 | X | — | — |
| Q1 2018 Jan 1, 2018 – Mar 31, 2018 | X | — | — |
| Q4 2017 Oct 1, 2017 – Dec 31, 2017 | X | — | — |
| Q3 2017 Jul 1, 2017 – Sep 30, 2017 | X | — | — |
| Q2 2017 Apr 1, 2017 – Jun 30, 2017 | X | — | — |
| Q1 2017 Jan 1, 2017 – Mar 31, 2017 | X | — | — |
| Q4 2016 Oct 1, 2016 – Dec 31, 2016 | X | — | — |
| Q3 2016 Jul 1, 2016 – Sep 30, 2016 | X | — | — |
| Q2 2016 Apr 1, 2016 – Jun 30, 2016 | X | — | — |
| Q1 2016 Jan 1, 2016 – Mar 31, 2016 | X | — | — |
| Q4 2015 Oct 1, 2015 – Dec 31, 2015 | X | — | — |
| Q3 2015 Jul 1, 2015 – Sep 30, 2015 | X | — | — |
| Q2 2015 Apr 1, 2015 – Jun 30, 2015 | X | — | — |
| Q1 2015 Jan 1, 2015 – Mar 31, 2015 | X | — | — |
| Q4 2014 Oct 1, 2014 – Dec 31, 2014 | X | — | — |
| Q3 2014 Jul 1, 2014 – Sep 30, 2014 | X | — | — |
| Q2 2014 Apr 1, 2014 – Jun 30, 2014 | X | — | — |
| Q2 2013 Apr 1, 2013 – Jun 30, 2013 | X | — | — |
| Q1 2013 Jan 1, 2013 – Mar 31, 2013 | X | — | — |
When does this rate change?
CMS publishes a fee schedule release every quarter (January, April, July, October), and each is versioned here. See what changed each release, or get an email when a new release moves rates.
Sources: CMS Medicare Physician Fee Schedule Relative Value Files.
Usage and related codes Copy link
How often 80048 is billed Copy link
Across Original Medicare in CY2024, 80048 ranked #65 of the 7,879 CPT codes billed to Medicare that year, by patients served or total allowed dollars. It repeats: a patient billed for it in 2024 was billed 1.7 times on average that year.
2024 Medicare fee-for-service national totals. They exclude Medicare Advantage, Medicaid and commercial volume, so real-world use runs higher. This is a calendar-year snapshot from the CMS Physician & Other Practitioners dataset, on a different cycle from the Q4 2026 fee schedule above.
Who bills 80048 to Medicare
Observed CY2024 Medicare fee-for-service billing, by the rendering clinician's CMS specialty. Each share is that specialty's slice of all observed services for this code that year.
Setting split that year: 100% Office (non-facility) · 0% facility. CMS publishes only this facility vs non-facility split, never the exact place of service. The Office (non-facility) figure does not identify urgent care or any other specific setting.
CY2024 Medicare fee-for-service only, from the CMS Physician & Other Practitioners dataset, which suppresses rows under 11 beneficiaries. We omit specialty groups with fewer than 30 observed clinicians, so the shares can fall short of 100%. Specialty and practice-type pages linked elsewhere on this page are curated code lists, not utilization claims.
Did this answer your question about CPT 80048?
Tell us what you were trying to work out and we'll answer you or build the page that does.
Source & method
Show sources
Hide
The lab amount comes from the Clinical Laboratory Fee Schedule record shown above. Its release and effective date are independent of the PFS release used for status evidence. Past releases are never edited, so these sources stay valid after CMS publishes a newer one. The commercial rates above are the only figures on this page that CMS did not publish. Payers published them in their own Transparency in Coverage files. Our methodology explains sourcing, parsing, versioning, and how we cross-check claims before we publish them.
Localis context written from primary sources: CMS Medicare Physician Fee Schedule Relative Value Files. Not derived from AMA CPT descriptor text.
Cite this rate
The citation names the release, so anyone can check it even after CMS publishes a newer one.
CPT 80048: $8.46 (CLFS Q4 2026; effective 2026-01-01). PUF_CLFS_CY2026_Q4V1.csv, row 645. Localis. https://localishealth.com/sources/clinical-lab-fee-schedule/2026/D