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Describe a service in plain words, or type a CPT/HCPCS code.

Effective Jan 1, 2024 through Mar 8, 2024. This is revision 1—CMS published revision 2 with rates effective Mar 9, 2024 (posted Apr 1, 2024).

CPT 80053 Medicare payment status

Full Metabolic Blood Panel

Priced under CLFS

80053 · PFS Q1 2024 · Historical

Status X is not separately payable under the PFS.

View applicable payment rules
View CMS source and method

CMS RVU24AJanuary 1 – March 8, 2024

PFS status evidence

Inspect PFS status evidence
Code
80053
Release
Q1 2024, revision 1
Result
Priced under CLFS

Citations

  • Shows this code’s PFS status (X). Result: Priced under CLFS.

    Physician relative value file (PPRRVU)CMS RVU24AJanuary 1 – March 8, 2024revision 1, since superseded

    This PFS record alone does not establish a $0 allowance or a coverage determination. Any amount from another schedule needs its own evidence.

    PPRRVU24_JAN.csv row 14,980 in rvu24a-updated-04-01-2024.zip

    In the CMS file

    Loading rows 14,978–14,982 of PPRRVU24_JAN.csv…

    Download rvu24a-updated-04-01-2024.zip from CMS File fingerprint 034f3aa88a63e6f7ca3859c09b3945dce139171a6fc5a710300fc7b815e9b65b

Plain-text summaryReport a problem

CPT 80053 has no published national rate. It carries status X (statutory exclusion) in the Q1 2024 release. The statutory definition of physician services does not include this item. The blank amount means unpriced, not $0.

Why is there no national PFS amount for 80053?

Its status indicator is X (statutory exclusion). The statutory definition of physician services does not include this item. Status X is not separately payable under the PFS.

About this code

One blood test measuring a standard group of substances: blood sugar, salts and minerals, and markers of kidney and liver function. It gives a broad check on several organ systems at once. Medicare reported 27.2 million services under this code in CY2024.

Plain-language context only—not the official CPT descriptor and not coding guidance

Payment considerations Copy link

Here are the inputs and payment rules that apply to this code. Each link takes you to the detail below.

Other payment indicators (9)
Facility/non-facility: Not determined, Professional/technical component: Does not apply, Bilateral adjustment: Does not apply, Multiple-procedure reduction: Does not apply, Assistant/co-surgeon treatment: Does not apply, Global surgery: Does not apply, NCCI same-day edits: Not determined, MUE behavior: Not determined, Contractor pricing: Does not apply.
Why would a Medicare claim for 80053 be denied or paid less?

These come from CMS indicators on this page, not general billing advice.

  • Its status indicator is X (statutory exclusion)—The statutory definition of physician services does not include this item. See status indicators

Payer-specific coverage and documentation rules live outside these files, so a claim that clears every check here can still be denied on other grounds.

Which billing rules and modifiers apply? Copy link

Global period: what 80053's fee already covers Copy link

XXX Does not apply

The global surgery concept does not apply to this code.

Can you bill it with another code? Copy link

Check a pair of codes Copy link

Enter a second CPT or HCPCS code billed on the same date of service. We'll check the current NCCI procedure-to-procedure edit for the pair.

See every current NCCI pair for 80053 →

Payment review for 80053 Copy link

Lab panels, their component tests, and specimen collection can be paid under different rules and schedules. Compare like with like, and keep the panel line separate from the blood draw.

What to check

  • Use the CLFS amount for the lab test instead of reading a blank PFS amount as zero.
  • Check component bundling and repeat-test rules against the NCCI edits in effect on the date of service.
  • Bill 36415 as its own collection line, and don’t multiply it by the number of tests in the panel.

Compare against 80048, 80050 and 36415: their amounts are in Related codes.

Sources: CMS Clinical Laboratory Fee Schedule; CMS Medicare NCCI Policy Manual (2026); CMS Medicare Claims Processing Manual (Pub. 100-04).

How has it changed? Copy link

Rate history by release Copy link

National Office (non-facility) amount for 80053 across quarterly releases.

Release Status Office Facility
Q4 2026 Oct 1, 2026 – present X — —
Q3 2026 Jul 1, 2026 – Sep 30, 2026 X — —
Q2 2026 Apr 1, 2026 – Jun 30, 2026 X — —
When does this rate change?

CMS publishes a fee schedule release every quarter (January, April, July, October), and each is versioned here. See what changed each release, or get an email when a new release moves rates.

Sources: CMS Medicare Physician Fee Schedule Relative Value Files.

Usage and related codes Copy link

How often 80053 is billed Copy link

Across Original Medicare in CY2024, 80053 ranked #5 of the 7,879 CPT codes billed to Medicare that year, by patients served or total allowed dollars. It repeats: a patient billed for it in 2024 was billed 2.1 times on average that year.

Beneficiaries
13.1M
Office + facility beneficiaries combined
Services
27.2M
Times it was billed
Allowed
$281.2M
Total Medicare allowed dollars
Compare: ↑ #4 more popular · 99233 ↓ #6 less popular · 99232

2024 Medicare fee-for-service national totals. They exclude Medicare Advantage, Medicaid and commercial volume, so real-world use runs higher. This is a calendar-year snapshot from the CMS Physician & Other Practitioners dataset, on a different cycle from the Q1 2024 fee schedule above.

Who bills 80053 to Medicare

Observed CY2024 Medicare fee-for-service billing, by the rendering clinician's CMS specialty. Each share is that specialty's slice of all observed services for this code that year.

Hematology/Oncology
23%
Family Medicine
22%
Internal Medicine
21%
Pathology
12%
NP/PA
11%

Setting split that year: 100% Office (non-facility) · 0% facility. CMS publishes only this facility vs non-facility split, never the exact place of service. The Office (non-facility) figure does not identify urgent care or any other specific setting.

CY2024 Medicare fee-for-service only, from the CMS Physician & Other Practitioners dataset, which suppresses rows under 11 beneficiaries. We omit specialty groups with fewer than 30 observed clinicians, so the shares can fall short of 100%. Specialty and practice-type pages linked elsewhere on this page are curated code lists, not utilization claims.

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Source & method

Show sources

This page uses CMS's Medicare Physician Fee Schedule Q1 2024 release (effective January 2024). National baselines use GPCI 1.000 and exclude sequestration. Whether a national amount exists depends on the status and CMS’s payment instructions; blank RVUs are never treated as zero. Past releases are never edited, so these sources stay valid after CMS publishes a newer one. Our methodology explains sourcing, parsing, versioning, and how we cross-check claims before we publish them.

Cite this rate

The citation names the release, so anyone can check it even after CMS publishes a newer one.

CPT 80053 National PFS baseline: No national PFS rate (Q1 2024; participating physician; whole service; GPCI 1.000; sequestration excluded). CMS RVU24A, PPRRVU24_JAN.csv row 14,980. Localis. https://localishealth.com/cpt/80053/2024/A/1