Transferrin Blood Test
CPT 84466
Ordered as part of an iron workup for anemia, or to assess iron overload and nutritional status.
No national payment amount
Status X is not separately payable under the PFS.
Did Medicare pay separately for CPT 84466 in Q2 2026?
Not at a published national rate. CPT 84466 carries status X (statutory exclusion) in the Q2 2026 release. The statutory definition of physician services does not include this item. Treat the blank amount as unpriced, not as $0.
How often 84466 is billed
Across Original Medicare in CY2024, 84466 ranked #504 of the 7,879 CPT codes billed to Medicare that year, ranked by patients served or total allowed dollars.
2024 Medicare fee-for-service only, national totals — Medicare Advantage, Medicaid and commercial volume are excluded, so real-world use runs higher. This is a calendar-year snapshot from the CMS Physician & Other Practitioners dataset, on a different cycle from the Q2 2026 fee schedule the rates above come from.
Common questions
Why is there no payment amount for 84466?
Its status indicator is X (statutory exclusion). The statutory definition of physician services does not include this item. The blank is deliberate: the amount is either unknown or paid under another provision, so reading it as $0 would be wrong.
Why would a Medicare claim for 84466 be denied or paid less?
Each item below comes from a CMS indicator on this page — not general billing advice.
- Its status indicator is X (statutory exclusion) — The statutory definition of physician services does not include this item. See status indicators
Payer-specific coverage and documentation rules live outside these files, so a claim that clears every check here can still be denied on other grounds.
When does this rate change?
CMS publishes a fee schedule release every quarter (January, April, July, October), and each is versioned here. See what changed each release, or get an email when a new release moves rates.
Sources: CMS Medicare Physician Fee Schedule Relative Value Files.
Saw this code on your bill?
What is a 84466 visit in patient-friendly terms?
In plain terms: Measures transferrin, the protein that ferries iron through the bloodstream from storage sites to the bone marrow where red cells are built. It is closely tied to total iron binding capacity, which estimates the same carrying capacity by a different route. Transferrin tends to climb when the body is short of iron and drop with chronic inflammation, liver disease, or poor nutrition. Think of an anemia workup where the doctor wants to know not just how much iron is in your blood right now, but how much capacity there is to carry it. That combination is what separates true iron deficiency from the anemia that comes with chronic illness. You'll typically see CPT 84466 on a bill or explanation of benefits (EOB) when a clinician performs or bills for this service.
How this amount is computed
amount = (work RVU × work GPCI + PE RVU × PE GPCI + MP RVU × MP GPCI) × conversion factor. National amounts use GPCI = 1.000. To price an RVU figure of your own, use the RVU-to-dollars converter.
| Component | RVU |
|---|---|
| Work RVU | blank |
| Practice expense RVU (non-facility) | blank |
| Practice expense RVU (facility) | blank |
| Malpractice RVU | blank |
Every rate combines three parts: work (the clinician’s time, skill and effort), practice expense (office overhead — higher when the service is done in a doctor’s own office), and malpractice (the share of liability-insurance cost). A blank means CMS publishes no national number for that part. Read it as unknown, and never as zero.
Rate history by release
National non-facility amount for 84466 across quarterly releases.
| Release | Status | Non-facility | Facility |
|---|---|---|---|
| Q3 2026 Jun 30, 2026 – present | X | — | — |
| Q2 2026 Mar 10, 2026 – Jun 29, 2026 | X | — | — |
| Q1 2026 Dec 29, 2025 – Mar 9, 2026 | X | — | — |
| Q4 2025 Sep 11, 2025 – Dec 28, 2025 | X | — | — |
| Q3 2025 Jun 5, 2025 – Sep 10, 2025 | X | — | — |
| Q2 2025 Jun 5, 2025 – Jun 4, 2025 | X | — | — |
| Q1 2025 Dec 23, 2024 – Jun 4, 2025 | X | — | — |
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Source & method
This is computed from CMS's Medicare Physician Fee Schedule Q2 2026 release (schedule pfs, effective April 2026). National amounts apply a GPCI of 1.000 and leave sequestration off. The status indicator decides payability, never the RVU values, so a blank RVU stays blank. Releases are immutable: a rate retrieved for a past quarter always reflects that release. Commercial and cash-pay figures anywhere on this page are arithmetic on the Medicare amount, using commonly cited reimbursement ranges. They're illustrative, and no nationwide claims database stands behind them.
Description written from primary sources: CMS Medicare Physician Fee Schedule Relative Value Files. Not derived from AMA CPT descriptor text.
Conversion factor $33.4009 read from the same file, row 11, column 26.
Use the (i) buttons next to each amount above for the exact row, columns, and math.
Cite this rate
This link keeps pointing at the Q2 2026 figures, even after a newer release lands.
CPT 84466 Medicare Physician Fee Schedule rate (Q2 2026). Localis. https://localishealth.com/cpt/84466/2026/B