Transferrin Blood Test
CPT 84466
Ordered as part of an iron workup for anemia, or to assess iron overload and nutritional status.
No national payment amount
Status X is not separately payable under the PFS.
Did Medicare pay separately for CPT 84466 in Q1 2018?
Not at a published national rate. CPT 84466 carries status X (statutory exclusion) in the Q1 2018 release. The statutory definition of physician services does not include this item. Treat the blank amount as unpriced, not as $0.
Source: Physician relative value file (Q1 2018) · effective January 2018 · materially updated Aug 4, 2026 · compact facts
How often 84466 is billed
Across Original Medicare in CY2024, 84466 ranked #504 of the 7,879 CPT codes billed to Medicare that year, ranked by patients served or total allowed dollars.
2024 Medicare fee-for-service only, national totals — Medicare Advantage, Medicaid and commercial volume are excluded, so real-world use runs higher. This is a calendar-year snapshot from the CMS Physician & Other Practitioners dataset, on a different cycle from the Q1 2018 fee schedule the rates above come from.
Common questions
Why is there no payment amount for 84466?
Its status indicator is X (statutory exclusion). The statutory definition of physician services does not include this item. The blank is deliberate: the amount is either unknown or paid under another provision, so reading it as $0 would be wrong.
Why would a Medicare claim for 84466 be denied or paid less?
Each item below comes from a CMS indicator on this page — not general billing advice.
- Its status indicator is X (statutory exclusion) — The statutory definition of physician services does not include this item. See status indicators
Payer-specific coverage and documentation rules live outside these files, so a claim that clears every check here can still be denied on other grounds.
When does this rate change?
CMS publishes a fee schedule release every quarter (January, April, July, October), and each is versioned here. See what changed each release, or get an email when a new release moves rates.
Sources: CMS Medicare Physician Fee Schedule Relative Value Files.
Saw this code on your bill?
What is a 84466 visit in patient-friendly terms?
In plain terms: Measures transferrin, the protein that ferries iron through the bloodstream from storage sites to the bone marrow where red cells are built. It is closely tied to total iron binding capacity, which estimates the same carrying capacity by a different route. Transferrin tends to climb when the body is short of iron and drop with chronic inflammation, liver disease, or poor nutrition. Think of an anemia workup where the doctor wants to know not just how much iron is in your blood right now, but how much capacity there is to carry it. That combination is what separates true iron deficiency from the anemia that comes with chronic illness. You'll typically see CPT 84466 on a bill or explanation of benefits (EOB) when a clinician performs or bills for this service.
How this amount is computed
amount = (work RVU × work GPCI + PE RVU × PE GPCI + MP RVU × MP GPCI) × conversion factor. National amounts use GPCI = 1.000. To price an RVU figure of your own, use the RVU-to-dollars converter.
| Component | RVU |
|---|---|
| Work RVU | blank |
| Practice expense RVU (non-facility) | blank |
| Practice expense RVU (facility) | blank |
| Malpractice RVU | blank |
Every rate combines three parts: work (the clinician’s time, skill and effort), practice expense (office overhead — higher when the service is done in a doctor’s own office), and malpractice (the share of liability-insurance cost). A blank means CMS publishes no national number for that part. Read it as unknown, and never as zero.
Rate history by release
National non-facility amount for 84466 across quarterly releases.
| Release | Status | Non-facility | Facility |
|---|---|---|---|
| Q3 2026 Jun 30, 2026 – present | X | — | — |
| Q2 2026 Mar 10, 2026 – Jun 29, 2026 | X | — | — |
| Q1 2026 Dec 29, 2025 – Mar 9, 2026 | X | — | — |
| Q4 2025 Sep 11, 2025 – Dec 28, 2025 | X | — | — |
| Q3 2025 Jun 5, 2025 – Sep 10, 2025 | X | — | — |
| Q2 2025 Jun 5, 2025 – Jun 4, 2025 | X | — | — |
| Q1 2025 Dec 23, 2024 – Jun 4, 2025 | X | — | — |
| Q4 2024 Aug 9, 2024 – Dec 22, 2024 | X | — | — |
| Q3 2024 May 3, 2024 – Aug 8, 2024 | X | — | — |
| Q2 2024 Mar 15, 2024 – May 2, 2024 | X | — | — |
| Q1 2024 Mar 11, 2023 – Mar 14, 2024 | X | — | — |
| Q4 2023 Aug 1, 2023 – Mar 10, 2023 | X | — | — |
| Q3 2023 May 10, 2023 – Jul 31, 2023 | X | — | — |
| Q2 2023 Feb 3, 2023 – May 9, 2023 | X | — | — |
| Q1 2023 Jan 30, 2023 – Feb 2, 2023 | X | — | — |
| Q4 2022 Jul 29, 2022 – Jan 29, 2023 | X | — | — |
| Q3 2022 Jun 17, 2022 – Jul 28, 2022 | X | — | — |
| Q2 2022 Feb 14, 2022 – Jun 16, 2022 | X | — | — |
| Q1 2022 Dec 15, 2021 – Feb 13, 2022 | X | — | — |
| Q4 2021 Aug 3, 2021 – Dec 14, 2021 | X | — | — |
| Q3 2021 Jun 10, 2021 – Aug 2, 2021 | X | — | — |
| Q2 2021 Feb 26, 2021 – Jun 9, 2021 | X | — | — |
| Q1 2021 Dec 29, 2020 – Feb 25, 2021 | X | — | — |
| Q4 2020 Oct 21, 2020 – Dec 28, 2020 | X | — | — |
| Q3 2020 Jun 18, 2020 – Oct 20, 2020 | X | — | — |
| Q2 2020 Apr 30, 2020 – Jun 17, 2020 | X | — | — |
| Q1 2020 Nov 8, 2019 – Apr 29, 2020 | X | — | — |
| Q4 2019 Aug 2, 2019 – Nov 7, 2019 | X | — | — |
| Q3 2019 May 3, 2019 – Aug 1, 2019 | X | — | — |
| Q2 2019 Mar 1, 2019 – May 2, 2019 | X | — | — |
| Q1 2019 Dec 13, 2018 – Feb 28, 2019 | X | — | — |
| Q4 2018 Aug 3, 2018 – Dec 12, 2018 | X | — | — |
| Q3 2018 Apr 30, 2018 – Aug 2, 2018 | X | — | — |
| Q2 2018 Feb 12, 2018 – Apr 29, 2018 | X | — | — |
| Q1 2018 Feb 9, 2018 – Feb 11, 2018 | X | — | — |
| Q4 2017 Aug 18, 2017 – Feb 8, 2018 | X | — | — |
| Q3 2017 May 3, 2017 – Aug 17, 2017 | X | — | — |
| Q2 2017 Feb 9, 2017 – May 2, 2017 | X | — | — |
| Q1 2017 Nov 14, 2016 – Feb 8, 2017 | X | — | — |
| Q4 2016 Aug 5, 2016 – Nov 13, 2016 | X | — | — |
| Q3 2016 May 17, 2016 – Aug 4, 2016 | X | — | — |
| Q2 2016 Feb 2, 2016 – May 16, 2016 | X | — | — |
| Q1 2016 Jan 21, 2016 – Feb 1, 2016 | X | — | — |
| Q4 2015 Oct 2, 2015 – Jan 20, 2016 | X | — | — |
| Q3 2015 May 15, 2015 – Oct 1, 2015 | X | — | — |
| Q2 2015 Feb 13, 2015 – May 14, 2015 | X | — | — |
| Q1 2015 Dec 23, 2014 – Feb 12, 2015 | X | — | — |
| Q4 2014 Aug 19, 2014 – Dec 22, 2014 | X | — | — |
| Q3 2014 May 15, 2014 – Aug 18, 2014 | X | — | — |
| Q2 2014 Mar 24, 2014 – May 14, 2014 | X | — | — |
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Source & method
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This is computed from CMS's Medicare Physician Fee Schedule Q1 2018 release (schedule pfs, effective January 2018). National amounts apply a GPCI of 1.000 and leave sequestration off. The status indicator decides payability, never the RVU values, so a blank RVU stays blank. Releases are immutable: a rate retrieved for a past quarter always reflects that release. Commercial and cash-pay figures anywhere on this page are arithmetic on the Medicare amount, using commonly cited reimbursement ranges. They're illustrative, and no nationwide claims database stands behind them. Our methodology covers all of this in depth — sourcing, parsing, versioning, and how claims are cross-checked before they ship.
Description written from primary sources: CMS Medicare Physician Fee Schedule Relative Value Files. Not derived from AMA CPT descriptor text.
Conversion factor $35.9996 read from the same file, row 11, column 25.
Use the (i) buttons next to each amount above for the exact row, columns, and math.
Cite this rate
This link keeps pointing at the Q1 2018 figures, even after a newer release lands.
CPT 84466 Medicare Physician Fee Schedule rate (Q1 2018). Localis. https://localishealth.com/cpt/84466/2018/A