# CPT 88342

> Medicare paid $102.43 for CPT 88342 in the office (non-facility) setting and $102.43 in a facility under the Q2 2022 Physician Fee Schedule, effective April 2022. These are the national allowed amounts before the ~2% sequestration cut and before locality (GPCI) adjustment. This price has been unchanged since Q1 2022, when it decreased 3.4%.

## What it is

A test in which a laboratory-made antibody is applied to a tissue slide to reveal whether a specific protein is present, followed by the pathologist's reading of the stained slide. The antibody carries a marker that produces visible color wherever its target protein sits, so the result is read as a pattern on the tissue rather than as a number. Immunohistochemistry is how pathologists identify what type of cell a tumor came from when appearance alone is ambiguous. This code covers the first antibody run on a given tissue block; further antibodies on the same block are reported separately.

## Selected release

- Release: Q2 2022 (2022 B)
- Effective: April 1 – June 30, 2022
- Status indicator: A
- Office (non-facility) national allowed amount: $102.43
- Facility national allowed amount: $102.43
- Sequestration: not applied

## RVUs and formula

- Work RVU: 0.70
- Office (non-facility) practice expense RVU: 2.24
- Facility practice expense RVU: 2.24
- Malpractice RVU: 0.02
- Conversion factor: 34.6062
- Formula: `(work_rvu × work_gpci + pe_rvu × pe_gpci + mp_rvu × mp_gpci) × conversion_factor`

## Source and citation

- Source: Physician relative value file (Q2 2022)
- CMS file: https://www.cms.gov/files/zip/rvu22b.zip
- Parsed file: PPRRVU22_APR.csv, row 15,778
- Canonical page: https://localishealth.com/cpt/88342/2022/A
- Release-specific citation URL: https://localishealth.com/cpt/88342/2022/B
- Last significant update: 2026-08-04T03:11:36+00:00