# CPT 78451

> The national PFS baseline was $296.94 for CPT 78451 in the office (non-facility) setting and $296.94 in a facility under the Q4 2025 Physician Fee Schedule, effective October 2025. These are the national allowed amounts before locality (GPCI) adjustment; sequestration is excluded. Across payment localities, both settings' amount is $259.38–$408.89. This price has been unchanged since Q1 2025, when it decreased 5.0%.

## Selected release

- Release: Q4 2025 (2025 D)
- Effective: October 1 – December 31, 2025
- Status indicator: A
- Office (non-facility) national allowed amount: $296.94
- Facility national allowed amount: $296.94
- Sequestration: not applied

## RVUs and formula

- Work RVU: 1.38
- Office (non-facility) practice expense RVU: 7.72
- Facility practice expense RVU: 7.72
- Malpractice RVU: 0.08
- Conversion factor: 32.3465
- Formula: `(work_rvu × work_gpci + pe_rvu × pe_gpci + mp_rvu × mp_gpci) × conversion_factor`

## Source and citation

- Source: Physician relative value file (Q4 2025)
- CMS file: https://www.cms.gov/files/zip/rvu25d-updated-09/11/2025.zip
- Parsed file: PPRRVU2025_Oct.csv, row 9,184
- Canonical page: https://localishealth.com/cpt/78451/2025/A
- Release-specific citation URL: https://localishealth.com/cpt/78451/2025/D
- Last significant update: 2026-08-04T03:15:45+00:00