# CPT 57421

> The national PFS baseline was $173.05 for CPT 57421 in the office (non-facility) setting and $118.71 in a facility under the Q3 2025 Physician Fee Schedule, effective July 2025. These are the national allowed amounts before locality (GPCI) adjustment; sequestration is excluded. Across payment localities, the office amount is $154.47–$213.45 and the facility amount is $107.03–$151.98. This price has been unchanged since Q1 2025, when it decreased 3.4%.

## Selected release

- Release: Q3 2025 (2025 C)
- Effective: July 1 – September 30, 2025
- Status indicator: A
- Office (non-facility) national allowed amount: $173.05
- Facility national allowed amount: $118.71
- Sequestration: not applied

## RVUs and formula

- Work RVU: 2.20
- Office (non-facility) practice expense RVU: 2.76
- Facility practice expense RVU: 1.08
- Malpractice RVU: 0.39
- Conversion factor: 32.3465
- Formula: `(work_rvu × work_gpci + pe_rvu × pe_gpci + mp_rvu × mp_gpci) × conversion_factor`

## Source and citation

- Source: Physician relative value file (Q3 2025)
- CMS file: https://www.cms.gov/files/zip/rvu25c-updated-06/05/2025.zip
- Parsed file: PPRRVU2025_Jul.csv, row 6,318
- Canonical page: https://localishealth.com/cpt/57421/2025/A
- Release-specific citation URL: https://localishealth.com/cpt/57421/2025/C
- Last significant update: 2026-08-04T03:15:26+00:00