# CPT 57421

> The national PFS baseline was $173.05 for CPT 57421 in the office (non-facility) setting and $118.71 in a facility under the Q1 2025 Physician Fee Schedule, effective January 2025. These are the national allowed amounts before locality (GPCI) adjustment; sequestration is excluded. Across payment localities, the office amount is $154.47–$213.45 and the facility amount is $107.03–$151.98. This is a 3.4% decrease from the previous quarter.

## Selected release

- Release: Q1 2025 (2025 A)
- Effective: January 1 – March 31, 2025
- Status indicator: A
- Office (non-facility) national allowed amount: $173.05
- Facility national allowed amount: $118.71
- Sequestration: not applied

## RVUs and formula

- Work RVU: 2.20
- Office (non-facility) practice expense RVU: 2.76
- Facility practice expense RVU: 1.08
- Malpractice RVU: 0.39
- Conversion factor: 32.3465
- Formula: `(work_rvu × work_gpci + pe_rvu × pe_gpci + mp_rvu × mp_gpci) × conversion_factor`

## Source and citation

- Source: Physician relative value file (Q1 2025)
- CMS file: https://www.cms.gov/files/zip/rvu25a-updated-01/10/2025.zip
- Parsed file: PPRRVU25_JAN.csv, row 12,229
- Canonical page: https://localishealth.com/cpt/57421/2025/A
- Release-specific citation URL: https://localishealth.com/cpt/57421/2025/A
- Last significant update: 2026-08-04T03:14:43+00:00