# CPT 49521

> The national PFS baseline was $705.15 for CPT 49521 in the office (non-facility) setting and $705.15 in a facility under the Q2 2025 Physician Fee Schedule, effective April 2025. These are the national allowed amounts before locality (GPCI) adjustment; sequestration is excluded. Across payment localities, both settings' amount is $620.54–$872.47. This price has been unchanged since Q1 2025, when it decreased 2.0%.

## Selected release

- Release: Q2 2025 (2025 B)
- Effective: April 1 – June 30, 2025
- Status indicator: A
- Office (non-facility) national allowed amount: $705.15
- Facility national allowed amount: $705.15
- Sequestration: not applied

## RVUs and formula

- Work RVU: 11.48
- Office (non-facility) practice expense RVU: 7.45
- Facility practice expense RVU: 7.45
- Malpractice RVU: 2.87
- Conversion factor: 32.3465
- Formula: `(work_rvu × work_gpci + pe_rvu × pe_gpci + mp_rvu × mp_gpci) × conversion_factor`

## Source and citation

- Source: Physician relative value file (Q2 2025)
- CMS file: https://www.cms.gov/files/zip/rvu25b-updated-06/05/2025.zip
- Parsed file: PPRRVU25_APR.csv, row 11,640
- Canonical page: https://localishealth.com/cpt/49521/2025/A
- Release-specific citation URL: https://localishealth.com/cpt/49521/2025/B
- Last significant update: 2026-08-04T03:14:58+00:00