# CPT 37221

> The national PFS baseline was $2,800.88 for CPT 37221 in the office (non-facility) setting and $464.82 in a facility under the Q4 2025 Physician Fee Schedule, effective October 2025. These are the national allowed amounts before locality (GPCI) adjustment; sequestration is excluded. Across payment localities, the office amount is $2,427.02–$3,851.07 and the facility amount is $408.59–$599.66. This price has been unchanged since Q1 2025, when it decreased 6.9%.

## Selected release

- Release: Q4 2025 (2025 D)
- Effective: October 1 – December 31, 2025
- Status indicator: A
- Office (non-facility) national allowed amount: $2800.88
- Facility national allowed amount: $464.82
- Sequestration: not applied

## RVUs and formula

- Work RVU: 9.75
- Office (non-facility) practice expense RVU: 74.63
- Facility practice expense RVU: 2.41
- Malpractice RVU: 2.21
- Conversion factor: 32.3465
- Formula: `(work_rvu × work_gpci + pe_rvu × pe_gpci + mp_rvu × mp_gpci) × conversion_factor`

## Source and citation

- Source: Physician relative value file (Q4 2025)
- CMS file: https://www.cms.gov/files/zip/rvu25d-updated-09/11/2025.zip
- Parsed file: PPRRVU2025_Oct.csv, row 4,474
- Canonical page: https://localishealth.com/cpt/37221/2025/A
- Release-specific citation URL: https://localishealth.com/cpt/37221/2025/D
- Last significant update: 2026-08-04T03:15:45+00:00